Name: 17α-Estradiol (Alfatradiol, a-Estradiol,17-epi Estradiol)
SKU: 57-91-0
Price: 83.57 USD
Availability: InStock

17α-Estradiol (Alfatradiol, a-Estradiol,17-epi Estradiol)

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17α-Estradiol (Alfatradiol, a-Estradiol,17-epi Estradiol)

Stock: In Stock
Model: 17α-Estradiol
SKU: 57-91-0

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Description
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Product Name: 17α-Estradiol

CAS No.: 57-91-0

Molecular Formula: C₁₈H₂₄O₂

Molecular Weight: 272.38

Purity: ≥99%

Solubility

DMF: 20 mg/ml

DMSO: 20 mg/ml

DMSO: PBS (pH 7.2) (1:4): 0.2 mg/ml

Ethanol: 2.5 mg/ml

IUPAC Name

(17α)-Estra-1, 3, 5(10)-triene-3, 17-diol

Synonyms

Αlpha-Estradiol; Estradiol 17α-Hydroxy Impurity; (17)-Estra-1, 3, 5(10)-triene-3, 17-diol; 1, 3, 5-Estratriene-3, 17α-diol; 13α-Methyl-1, 3, 5(10)-gonatriene-3, 17α-diol; 17-Epiestradiol; 17α-Oestradiol; 3, 17-Dihydroxyestratriene; 3, 17α-Dihydroxyoestra-1, 3, 5(10)-triene; Alfatradiol; Epiestrol; Estra-1, 3, 5(10)-triene-3, 17α-diol; NSC 20293;

17α-Estradiol is a less active isomer than its counterpart, displaying 100-fold lower estrogenic activity relative to 17β-estradiol.

It can inhibit 5α-reductase, which plays a role in regulating hair growth. 17α -estradiol is reported to activate the MAPK/ERK and PI3K-Akt signaling pathways via activation of the estrogen receptor-X and has been shown to be neuroprotective after an ischemic stroke and oxidative stress and in transgenic mice with Alzheimer’s disease.

Comparison of the efficacy and safety of topical minoxidil and topical alfatradiol in the treatment of androgenetic alopecia in women. The Efficacy and Safety of 17α-Estradiol (0.025%) Solution on Female Pattern Hair Loss: Single Center, Open-Label, Non-Comparative, Phase IV Study.

17α-Estradiol (Alfatradiol, a-Estradiol,17-epi Estradiol)

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